纺织学报 ›› 2019, Vol. 40 ›› Issue (05): 102-106.doi: 10.13475/j.fzxb.20180500905

• 染整与化学品 • 上一篇    下一篇

可溶性止血医用棉纱布的制备及其性能

钱璐敏1, 张斌1,2()   

  1. 1.东华大学 纺织学院, 上海 201620
    2.东华大学 纺织面料技术教育部重点实验室, 上海 201620
  • 收稿日期:2018-05-02 修回日期:2019-01-02 出版日期:2019-05-15 发布日期:2019-05-21
  • 通讯作者: 张斌
  • 作者简介:钱璐敏(1993—),女,硕士生。主要研究方向为医用纺织材料的改性与处理。

Preparation and characterization of soluble hemostatic medical cotton gauze

QIAN Lumin1, ZHANG Bin1,2()   

  1. 1. College of Textiles, Donghua University, Shanghai 201620, China
    2. Key Laboratory of Textile Science and Technology, Ministry of Education, Donghua University, Shanghai 201620, China
  • Received:2018-05-02 Revised:2019-01-02 Online:2019-05-15 Published:2019-05-21
  • Contact: ZHANG Bin

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摘要：

为提高羧甲基化医用棉纱布的可溶性,发挥其止血作用,采用单因素法探究溶媒法制备工艺。考察了碱化预处理的碱液质量分数、碱化时间和醚化反应的氯乙酸质量分数、醚化时间和醚化温度等因素对棉纱布溶解性能的影响,确定出较佳制备工艺,并借助红外光谱仪、扫描电子显微镜对所制得的可溶性止血纱布进行表征。结果表明:在较佳的可溶性止血纱布制备工艺下,即碱化预处理时碱液质量分数为20%、碱化时间为30 min,醚化时氯乙酸质量分数为10.5%、醚化时间为4 h、醚化温度为70 ℃,棉纱布完全溶解所需时间为4 h;棉纱布发生了羧甲基化反应,羧甲基化后纤维直径增加。

关键词: 医用纱布, 羧甲基化, 溶媒法, 溶解性能

Abstract:

In order to improve the solubility of carboxymethyl medical cotton gauze to achieve good hemostatic effect, single factor analytical method was adopted to investigate the process conditions of solvent medium method. The influence of the mass fraction of sodium hydroxide and time of alkalization pre-treatment, the mass fraction of chloroacetic acid, temperature and time of etherification reaction on the solubility of cotton gauze were studied. The optimum preparation processes were obtained and the soluble hemostatic gauzes were characterized by Fourier transform infrared spectrometer and scanning electronic microscopy. The results show that the optimum soluble hemostatic gauzes are produced under the condition of 20% mass fraction of sodium hydroxide and alkalization pre-treatment for 30 min, 10.5% mass fraction of chloroacetic acid, etherification at 70 ℃ for 4 h, while the dissolution time is 4 h. The cotton gauze is carboxymethylated, and the diameters of fibers increase after carboxymethylation.

Key words: medical gauze, carboxymethylation, solvent medium method, solubility

中图分类号: 

  • TS101.4

表1

碱液质量分数对纱布溶解性能影响"

碱液质量分数/% 溶解时间/h 碱液质量分数/% 溶解时间/h
10.0 不溶解 22.5 13.0
15.0 未完全溶解 25.0 13.5
16.0 12.5 27.5 13.5
20.0 8.5

表2

碱化时间对纱布溶解性能影响"

碱化时间/min 溶解时间/h 碱化时间/min 溶解时间/h
5 未完全溶解 45 8.2
15 12.0 60 9.8
30 7.2

表3

氯乙酸质量分数对纱布溶解性能影响"

氯乙酸质量分数/% 溶解时间/h 氯乙酸质量分数/% 溶解时间/h
3.5 不溶解 12.0 7.0
7.0 7.8 13.5 11.7
8.5 6.0 16.0 不溶解
10.5 4.2

表4

醚化时间对纱布溶解性能影响"

醚化时间/h 溶解时间/h 醚化时间/h 溶解时间/h
1 未完全溶解 4 6.0
2 未完全溶解 4 6.0
3 8.8 5 6.2
3 7.2 6 9.3

表5

醚化温度对纱布溶解性能影响"

醚化温度/℃ 溶解时间/h 醚化温度/℃ 溶解时间/h
40 不溶解 70 4.0
50 未完全溶解 75 9.2
60 8.5 80 12.8
65 6.0

图1

医用棉纱布的傅里叶变换红外光谱图"

图2

医用棉纱布扫描电子显微镜照片(×5 000)"

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