Abstract: To find an effective way for wool shrinkproofing,four alkaline proteases—Savinase,Esperase,Woolase and Papaya protease were selected to treat wool woven fabric for shrink-resistance and hydrogen peroxide was used as reagent in the pretreatment.The effect of the pretreatment on the wool shrinkproofing with protease was investigated.Especially it demonstrated by lowering the temperature of H_2O_2 treatment and adding activator A for H_2O_2 the loss of wool fiber strength by the pretreatment was reduced remarkably.Experiments revealed that the wool woven fabric treated by H_2O_2-enzyme system was imparted better shrinkproofing effect,but it exhibited rather serious strength loss of the wool fiber in general.However,combined use of two kinds or more enzymes plus protective agent A could reduce the strength loss of wool fiber.