Abstract: The effect of different polyester fabric structures(plain,twill and satin of the woven,jersey and interlock of the knitted) on the blood-compatibility of the fabric was studied by kinetic clotting,blood-coagulation factor and platelet adhesion experiments.The mathematical model of fuzzy comprehensive evaluation was used to characterize the total blood-compatibility.The experimental results indicated that the satin woven is not easy to cause the blood-coagulation and has better blood-compatibility.Meanwhile,the biological mechanics performance of different polyester fabric structures was characterized by permeability, void content,tensile strength,and bursting strength and so forth.The influence of fabric structure on its blood-compatibility and biological mechanics performance was discussed preliminarily.