Abstract: For accurate computation of the dye uptake rate of the fiber,this paper has developed a kinetics model for simulating the dye uptake rate by using multiple curve-fitting in combination with experimental data analysis on the basis of Hill equation.Knitted fabrics are dyed with Reactive Red RR,Weak Acid Green GS and Disperse Crimson S-2GFL respectively and the dye uptake rates at different times of these three groups of dyes are computed using this kinetics model and Hill equation and the results obtained are compared with the practical values measured.It showed that this new model is slightly advantageous over Hill equation,and in particular,the predicted dye uptake rate by the model is more agreeable with the actual value when up-taking of dye nearing the state of balance.