β-环糊精接枝棉织物包合药物的研究

纺织学报 ›› 2010, Vol. 31 ›› Issue (7): 64-68.

β-环糊精接枝棉织物包合药物的研究

朱平^1,2; 原新²; 张林²; 张建波²

1.新型纺织材料绿色加工及其功能化教育部重点实验室(武汉纺织大学) 2.青岛大学纤维新材料及现代纺织国家重点实验室培育基地

收稿日期:2009-09-01 修回日期:2010-01-17 出版日期:2010-07-15 发布日期:2010-07-15
通讯作者: 朱平

Study on inclusion medicine of cotton fabric grafted with β-cyclodextrin

ZHu Ping^1,2; YUAN Xing²; ZHANG Lin²; ZHANG Jianbo²

1. Key Laboratory of Green Processing and Functional Textiles of New Textile Materials (Wuhan Textile University), Ministry of Education 2. State Key Laboratory of New Fiber Materials & Modern Textile, Qingdao University

Received:2009-09-01 Revised:2010-01-17 Online:2010-07-15 Published:2010-07-15
Contact: ZHU ping

摘要/Abstract

摘要：

在碱性条件下使用环氧氯丙烷将β-环糊精接枝到棉织物上。利用β-环糊精的包合性制备了包合药物(丁香酚)的功能性棉织物,测定了其药物包合量并考察了包合药物在水溶液中的稳定性能和释放性能。结果表明,每克织物上的药物包合量为18.5 µg。在处于人体体温时,经β-环糊精整理的棉织物上丁香酚的释放达到理想状态。在30℃的水溶液中,当放置时间超过150 min,经β-环糊精整理的棉织物上包合丁香酚的释放基本达到平衡。

Abstract:

β-cyclodextrin was grafted onto the cotton fabric with epichlorohydrin in alkaline conditions. The functional cotton fabric which included medicine (eugenol) was produced with the inclusion capability of β-cyclodextrin. The content of the medicine was measured, and its stability and release capability in water were investigated. The results showed that the new cotton fabric included 18.5 µg medicine per gram. The release of the eugenol was at a good state when the cotton fabric was placed at the temperature of human body, and the eugenol release was nearly balanced over 150 min in water at 30℃.

朱平;原新;张林;张建波. β-环糊精接枝棉织物包合药物的研究[J]. 纺织学报, 2010, 31(7): 64-68.

ZHu Ping;YUAN Xing;ZHANG Lin;ZHANG Jianbo. Study on inclusion medicine of cotton fabric grafted with β-cyclodextrin[J]. JOURNAL OF TEXTILE RESEARCH, 2010, 31(7): 64-68.

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