壳聚糖纤维的理化性能和生物活性研究进展

doi:10.13475/j.fzxb.20180406107

摘要/Abstract

摘要：

为促进壳聚糖纤维在医疗和卫生产品中的应用,开发壳聚糖基功能纺织材料和先进医用纺织品,总结了壳聚糖纤维的理化特性及其吸附铜离子和锌离子的性能,分析了壳聚糖纤维的细胞活性、生物相容性及其在与伤口、血液、人体组织接触过程中产生的止血、抗菌、抑制基质金属蛋白酶、促进伤口愈合等生物活性。指出壳聚糖的氨基多糖结构及其对体液中金属离子的吸附性能使壳聚糖纤维和壳聚糖基纺织品在医用止血材料、伤口敷料、面膜制品、日用卫生品、抗菌纺织品等领域起到止血、抗菌、排毒、促愈、美白等生物活性和应用功效,具有很高的应用价值。

关键词: 甲壳素, 壳聚糖, 功能纤维, 医用敷料, 生物医用材料, 生物活性

Abstract:

In order to promote the application of chitosan fibers in medical and hygiene products, and develop functional textile materials and advanced medical textile products, this paper summarized the chemical and physical properties of chitosan fibers and their absorption properties for copper and zinc ions, and analyzed their cell activities, biocompatibilities and the various bioactivities while in contact with wound, blood and tissue, such as haemostasis, antimicrobial, enzyme inhibition, wound healing promotion, et al. It was pointed out that the glucosamine structure and the capability to bind metal ions play an important role in haemostasis, antimicrobial, detoxication, wound healing promotion, whitening and other bioactivities and functionalities, which are highly valuable in medical haemostatic materials, wound dressings, face masks, hygiene products and antimicrobial textile products.

Key words: chitin, chitosan, functional fiber, wound dressing, biomedical material, biological activity

中图分类号:

TS131.9

秦益民. 壳聚糖纤维的理化性能和生物活性研究进展[J]. 纺织学报, 2019, 40(05): 170-176.

QIN Yimin. Physicochemical properties and bioactivities of chitosan fibers[J]. Journal of Textile Research, 2019, 40(05): 170-176.

图/表 2

图1

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乙酰度/%	铜离子质量分数/%	—NH₂与Cu(II)的量比
0.86	8.2	2.9
36.6	5.4	2.9
60.8	3.6	2.8
97.2	0.6	1.2