纺织学报 ›› 2022, Vol. 43 ›› Issue (10): 16-23.doi: 10.13475/j.fzxb.20210906708

• 纤维材料 • 上一篇    下一篇

聚吡咯/丝素导电纳米纤维膜的制备及其性能

俞杨销1, 李枫1, 王煜煜1, 王善龙1, 王建南1,2, 许建梅1,2()   

  1. 1.苏州大学 纺织与服装工程学院, 江苏 苏州 215021
    2.苏州大学 纺织行业医疗健康用蚕丝制品重点实验室, 江苏 苏州 215123
  • 收稿日期:2021-09-06 修回日期:2022-03-17 出版日期:2022-10-15 发布日期:2022-10-28
  • 通讯作者: 许建梅
  • 作者简介:俞杨销(1998—),男,硕士生。主要研究方向为蚕丝蛋白生物医用材料。
  • 基金资助:
    中国纺织工业联合会科技指导性项目(2018023)

Preparation and properties of polypyrole/silk fibroin conductive nanofiber membranes

YU Yangxiao1, LI Feng1, WANG Yuyu1, WANG Shanlong1, WANG Jiannan1,2, XU Jianmei1,2()   

  1. 1. College of Textile and Clothing Engineering, Soochow University, Suzhou, Jiangsu 215021, China
    2. Key Laboratory of Textile Industry for Silk Products in Medical and Health Use, Soochow University, Suzhou, Jiangsu 215123, China
  • Received:2021-09-06 Revised:2022-03-17 Published:2022-10-15 Online:2022-10-28
  • Contact: XU Jianmei

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摘要：

为开发具有一定导电性的组织再生材料,采用静电纺丝法制备了丝素纳米纤维膜,通过原位氧化聚合获得了聚吡咯/丝素导电性纳米纤维膜,探究了纺丝参数对纳米纤维膜表面形貌的影响,利用四探针测试仪测试了纳米纤维膜的导电性,借助红外光谱仪对纳米纤维膜化学结构进行了表征。结果表明:在质量浓度为0.16 g/mL,推注速度为0.2 mL/h,电压为20 kV,滚筒转速为1 000 r/min的条件下,制备的丝素纳米纤维膜表面规整,珠状物少,纤维平均直径为(520.70±140.81) nm;在吡咯单体浓度为0.3 mol/L,掺杂剂浓度为0.3 mol/L,吡咯单体与FeCl3的量比为1∶2,聚合时间为6 h条件下,制备的聚吡咯/丝素导电性纳米纤维膜保留了丝素纳米纤维膜原有的纳米纤维结构,电导率达到(0.44±0.07) S/cm。

关键词: 聚吡咯, 丝素蛋白, 静电纺丝, 原位氧化聚合, 导电纳米纤维膜

Abstract:

In order to develop tissue regeneration materials with certain electrical conductivity, we prepared silk fibroin nanofiber membranes using electrospinning and further polypyrrole/silk fibroin conductive nanofiber membranes by in-situ oxidative polymerization. The effect of spinning parameters on the surface morphology of nanofiber membrane was studied. The electrical conductivity of nanofiber membrane was tested by the four-point probe. FT-IR spectrometer was used to characterize the chemical structure of nanofiber membrane. The results showed that silk fibroin nanofiber membranes have an even surface with less beads, with an average fiber diameter of (520.70±140.81) nm, when solution concentration was 0.16 g/mL, flow rate 0.2 mL/h, voltage 20 kV, rotating speed 1 000 r/min. Polypyrrole/silk fibroin conductive nanofiber membranes was prepared by in-situ oxidative polymerization, and it retains its original nano fiber structure, and the electrical conductivity is (0.44±0.07) S/cm, when the pyrrole concentration was 0.3 mol/L, dopant concentration 0.3 mol/L, the ratio of fixed pyrrole to oxidant 1∶2, and the polymerization time 6 h.

Key words: polypyrrole, silk fibroin, electrospinning, in-situ oxidative polymerization, conductive nanofiber membrane

中图分类号: 

  • TS101.4

图1

不同纺丝液质量浓度的SF纳米纤维膜表面形貌(×3 000)和直径分布图"

图2

不同纺丝液推注速度的SF纳米纤维膜表面形貌(×3 000)和直径分布图"

图3

不同纺丝电压的SF纳米纤维膜表面形貌(×3 000)和直径分布图"

图4

不同滚筒转速的SF纳米纤维膜表面形貌照片(×3 000)和直径分布图"

图5

PPy聚合过程 注:A-表示氧化剂所带的阴离子; B-表示掺杂剂所带的阴离子。"

图6

PPy与SF大分子链的相互作用"

图7

不同量比的PPy/SF纳米纤维膜表面形貌(×2 000)"

图8

不同物质的量比的PPy/SF纳米纤维膜电导率"

图9

试样的红外光谱图"

[1] ESLAHI N, REZA M, JOGHATAEI M T, et al. The effects of poly L-lactic acid nanofiber scaffold on mouse spermatogonial stem cell culture[J]. International JournaL of Nanomedicine, 2013, 8: 4563-4576.
[2] 贾琳, 陈莉娜, 张海霞, 等. 聚氨酯/胶原蛋白复合纳米纤维支架的性能[J]. 纺织学报, 2016, 37(8): 1-6.
JIA Lin, CHEN Li'na, ZHANG Haixia, et al. Performance of composite polyurethane/collagen nanofiber scaffolds[J]. Journal of Textile Research, 2016, 37(8): 1-6.
doi: 10.1177/004051756703700101
[3] ALTMAN G H, DIAZ F, JAKUBA C. Silk-based biomaterials[J]. Biomaterials, 2003, 24(3): 401-416.
pmid: 12423595
[4] 姜雨淋, 王卉, 张克勤. 生物3D打印用丝素蛋白基凝胶墨水的研究进展[J]. 纺织学报, 2021, 42(11): 1-8.
JIANG Yulin, WANG Hui, ZHANG Keqin. Research progress of silk fibroin-based hydrogel bioinks for 3D bio-printing[J]. Journal of Textile Research, 2021, 42(11): 1-8.
doi: 10.1177/004051757204200101
[5] LI X F, ZHANG Q, LUO Z W, et al. Biofunctionalized silk fibroin nanofibers for directional and long neurite outgrowth[J]. Biointerphases, 2019. DOI: 10.1063/1.5120738.
doi: 10.1063/1.5120738
[6] SCHMIDT C E, SHASTRI V R, VACANTI J P, et al. Stimulation of neurite outgrowth using an electrically conducting polymer[J]. Proceedings of the National Academy of Sciences of the United States of America, 1997, 94(17): 8948-8953.
pmid: 9256415
[7] LEE M H, PARK Y J, HONG S H, et al. Pulsed electrical stimulation enhances consistency of directional migration of adipose-derived stem cells[J]. Cells, 2021. DOI: 10.3390/cells10112846.
doi: 10.3390/cells10112846
[8] LONG Y, LI J, YANG F, et al. Wearable and implantable electroceuticals for therapeutic electrostimulations[J]. Advanced Science, 2020. DOI: 10.1002/advs.202004023.
doi: 10.1002/advs.202004023
[9] FUNK R H W. Endogenous electric fields as guiding cue for cell migration[J]. Frontiers in Physiology, 2015. DOI: 10.3389/fphys.2015.00143.
doi: 10.3389/fphys.2015.00143
[10] VAITKUVIENE A, KASETA V, VORONOVIC J, et al. Evaluation of cytotoxicity of polypyrrole nanoparticles synthesized by oxidative polymerization[J]. Journal of Hazardous Materials, 2013, 250: 167-174.
[11] KIM S, OH W K, JEONG Y S, et al. Cytotoxicity of, and innate immune response to, size-controlled polypyrrole nanoparticles in mammalian cells[J]. Biomaterials, 2011, 32(9): 2342-2350.
doi: 10.1016/j.biomaterials.2010.11.080 pmid: 21185594
[12] SUN B B, ZHOU Z F, LI D W, et al. Polypyrrole-coated poly(L-lactic acid-co-epsilon-caprolactone)/silk fibroin nanofibrous nerve guidance conduit induced nerve regeneration in rat[J]. Materials Science & Engineering C-Materials for Biological Applications, 2019, 94: 190-199.
[13] ZHAO Y H, NIU C M, SHI J Q, et al. Novel conductive polypyrrole/silk fibroin scaffold for neural tissue repair[J]. Neural Regeneration Research, 2018, 13(8): 1455-1464.
doi: 10.4103/1673-5374.235303
[14] ZHAO Y H, LIANG Y Y, DING S P, et al. Application of conductive PPy/SF composite scaffold and electrical stimulation for neural tissue engineering[J]. Biomaterials, 2020, 255: 120-164.
[15] LEE J Y, BASHUR C A, GOLDSTEIN A S, et al. Polypyrrole-coated electrospun PLGA nanofibers for neural tissue applications[J]. Biomaterials, 2009, 30(26): 4325-4335.
doi: 10.1016/j.biomaterials.2009.04.042 pmid: 19501901
[16] XU Y X, HUANG Z B, PU X M, et al. Fabrication of chitosan/polypyrrole-coated poly(L-lactic acid)/polycaprolactone aligned fibre films for enhancement of neural cell compatibility and neurite growth[J]. Cell Proliferation, 2019. DOI: 10.1111/cpr.12588.
doi: 10.1111/cpr.12588
[17] QI F Y, WANG Y Q, MA T, et al. Electrical regulation of olfactory ensheathing cells using conductive polypyrrole/chitosan polymers[J]. Biomaterials, 2013, 34(7): 1799-1809.
doi: 10.1016/j.biomaterials.2012.11.042 pmid: 23228424
[18] LIANG Y S, MITRIASHKIN A, LIM T T, et al. Conductive polypyrrole-encapsulated silk fibroin fibers for cardiac tissue engineering[J]. Biomaterials, 2021. DOI: 10.1016/j.biomaterials.2021.12100.
doi: 10.1016/j.biomaterials.2021.12100
[19] 李永舫. 导电聚吡咯的研究[J]. 高分子通报, 2005(4): 51-57.
LI Yongfang. Studies on conducting polypyrrole[J]. Polymer Bulletin, 2005(4): 51-57.
[20] XIA Y Y, LU Y. Fabrication and properties of conductive conjugated polymers/silk fibroin composite fibers[J]. Composites Science and Technology, 2008, 68(6): 1471-1479.
doi: 10.1016/j.compscitech.2007.10.044
[21] 于波, 徐学诚. 聚吡咯结构与导电性能的研究[J]. 华东师范大学学报(自然科学版), 2014(4): 77-87.
YU Bo, XU Xuecheng. Structure-conductive property relationship of polypyrrole[J]. Journal of East China Normal University (Natural Science Edition), 2014(4): 77-87.
[22] YURTSEVER M, YURTSEVER E. Structural studies of polypyrroles: I: an ab-initio evaluation of bonding through alpha and beta carbons[J]. Synthetic Metals, 1999, 98(3): 221-227.
doi: 10.1016/S0379-6779(98)00195-7
[23] HAN F, LIU S, LIU X, et al. Woven silk fabric-reinforced silk nanofibrous scaffolds for regenerating load-bearing soft tissues[J]. Acta Biomaterialia, 2014, 10(2): 921-930.
doi: 10.1016/j.actbio.2013.09.026 pmid: 24090985
[24] JIN X, WANG H, LIU Y M, et al. Hydrogen-bonding power interfacial load transfer of carbon fabric/polypyrrole composite pseudosupercapacitor electrode with improved electrochemical stability[J]. Applied Surface Science, 2019, 470: 783-791.
doi: 10.1016/j.apsusc.2018.11.125
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