Abstract: The purpose of this paper is to research effects of heat setting temperature on the properties of knitted polyester fabrics,especially the effect on anti-blood coagulation.The structures,activated partial thromboplastin time(APTT),prothrombin time(PT),blood platelet adherence property,water-absorbing property and dyeing property were tested on heat-set knitted polyester fabrics at different temperatures.The results showed that with rising of the heat setting temperature,the shrinkage rate of the fabric in transverse and machine directions increases.The water-absorption,anti-blood coagulation and dyeing properties of the fabric become the worst when heat setting is conducted at 150℃.By comparison of APTT and PT,can see that the heat setting of the fabric greatly inhibits its activation of exogenous coagulation factor PT.