Abstract: The preparation and stability of cellulose LiCl/DMAc（lithium chloride/N,N-dimethylacetamide） solution were studied .The results showed that: The cellulose of activated were added to the LiCl / DMAc system which formed by LiCl dissolved in DMAc, and stirrd certain period of time at 100 ℃ then cooled to room temperature stirring for several hours, the uniformly transparent cellulose LiCl / DMAc solution will be geted. The greater the concentration of cellulose, the longer the time required heat stirring and room temperature stirring; Similarly, the bigger the polymerization degree of cellulose , the worse the dissolved effection; The cellulose swelling only insoluble when LiCl includes crystal water, moreover when the quality score of LiCl surpasses 6%, the cellulose can be dissolved completely,and its content need to improve with the Content of cellulose . In addition, by studying the rate of change of the viscosity of cellulose LiCl / DMAc solution over time at different temperatures, come in lower than 50 ℃, the solution is very stable within 30 days; solution heated to 100 ℃, may stabilize 15 hours of the conclusion there.