Abstract: In order to successfully apply the foam technology to the process of textile dyeing, the composition of dyeing solution and parameters the foam properties were firstly analyzed. It was found that stabilizer, temperature, stirring speed, inorganic salts et al all have influence on foam properties, at the same time, the relationship between the surface properties of the foam and the micro-mechanism was analyzed. The Plackett-Burma (PB) design and central composite design (Central Composite Design) response surface method were used to design experiment when foam dyeing experiments on cotton fabric were carried out, the main factors affecting the foam dyeing were investigated, and optimum foam dyeing formula was obtained. When Reactive Red (DB150%) is fixed at 2g/L , the optimization process of K/S is as follows: sodium dodecyl sulfate 5g/L, sodium carboxymethyl cellulose 1g/ L, sodium alginate, 0.2g/ L, urea, 20g/L, sodium carbonate 3g/L, sodium chloride 5.74g/L, stirring speed 2700r/min, curing temperature 159℃, curing time 2min. Then the optimization process was repeated later for several times. It was found that difference of the value of K/S between samples is very small, and level of dyeing cloth is also good.