Journal of Textile Research ›› 2019, Vol. 40 ›› Issue (05): 102-106.doi: 10.13475/j.fzxb.20180500905

• Dyeing and Finishing & Chemicals • Previous Articles     Next Articles

Preparation and characterization of soluble hemostatic medical cotton gauze

QIAN Lumin1, ZHANG Bin1,2()   

  1. 1. College of Textiles, Donghua University, Shanghai 201620, China
    2. Key Laboratory of Textile Science and Technology, Ministry of Education, Donghua University, Shanghai 201620, China
  • Received:2018-05-02 Revised:2019-01-02 Online:2019-05-15 Published:2019-05-21
  • Contact: ZHANG Bin E-mail:zhangbin@dhu.edu.cn

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Abstract:

In order to improve the solubility of carboxymethyl medical cotton gauze to achieve good hemostatic effect, single factor analytical method was adopted to investigate the process conditions of solvent medium method. The influence of the mass fraction of sodium hydroxide and time of alkalization pre-treatment, the mass fraction of chloroacetic acid, temperature and time of etherification reaction on the solubility of cotton gauze were studied. The optimum preparation processes were obtained and the soluble hemostatic gauzes were characterized by Fourier transform infrared spectrometer and scanning electronic microscopy. The results show that the optimum soluble hemostatic gauzes are produced under the condition of 20% mass fraction of sodium hydroxide and alkalization pre-treatment for 30 min, 10.5% mass fraction of chloroacetic acid, etherification at 70 ℃ for 4 h, while the dissolution time is 4 h. The cotton gauze is carboxymethylated, and the diameters of fibers increase after carboxymethylation.

Key words: medical gauze, carboxymethylation, solvent medium method, solubility

CLC Number: 

  • TS101.4

Tab.1

Influence of mass fraction of sodium hydroxide on solubility of gauze"

碱液质量分数/% 溶解时间/h 碱液质量分数/% 溶解时间/h
10.0 不溶解 22.5 13.0
15.0 未完全溶解 25.0 13.5
16.0 12.5 27.5 13.5
20.0 8.5

Tab.2

Influence of alkalization time on solubility of gauze"

碱化时间/min 溶解时间/h 碱化时间/min 溶解时间/h
5 未完全溶解 45 8.2
15 12.0 60 9.8
30 7.2

Tab.3

Influence of mass fraction of chloroacetic acid on solubility of gauze"

氯乙酸质量分数/% 溶解时间/h 氯乙酸质量分数/% 溶解时间/h
3.5 不溶解 12.0 7.0
7.0 7.8 13.5 11.7
8.5 6.0 16.0 不溶解
10.5 4.2

Tab.4

Influence of etherification time on solubility of gauze"

醚化时间/h 溶解时间/h 醚化时间/h 溶解时间/h
1 未完全溶解 4 6.0
2 未完全溶解 4 6.0
3 8.8 5 6.2
3 7.2 6 9.3

Tab.5

Influence of etherification temperature on solubility of gauze"

醚化温度/℃ 溶解时间/h 醚化温度/℃ 溶解时间/h
40 不溶解 70 4.0
50 未完全溶解 75 9.2
60 8.5 80 12.8
65 6.0

Fig.1

FT-IR spectra of medical cotton gauze"

Fig.2

SEM images of medical cotton gauze before (a) and after (b) modification(×5 000)"

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