Journal of Textile Research ›› 2020, Vol. 41 ›› Issue (05): 1-7.doi: 10.13475/j.fzxb.20190407407

• Fiber Materials •     Next Articles

Preparation and photodynamic antimicrobial properties of hypocrellinpoly(methyl methacrylate-co-methacrylic acid) nanofibers

WANG Tingting1, LIU Liang1, CAO Xiuming2, WANG Qingqing1,2()   

  1. 1. Key Laboratory of Eco-Textiles (Jiangnan University), Ministry of Education, Wuxi, Jiangsu 214122, China
    2. Jiangsu Sunshine Co., Ltd., Wuxi, Jiangsu 214400, China
  • Received:2019-04-28 Revised:2020-02-03 Online:2020-05-15 Published:2020-06-02
  • Contact: WANG Qingqing E-mail:qqwang@jiangnan.edu.cn

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Abstract:

To overcome the limitation of antibiotic drugs in the treatment of drug resistant strains, photosensitizer hypocrellin(Hc)was added to the poly(methyl methacrylate-co-methacrylic acid) electrospinning solution to prepare the photodynamic broad-spectrum antibacterial nanofibrous membrane. The overall morphology, wettability, chemical structure and thermostability of the nanofibers before and after the addition of Hc were compared by scanning electron microscopy, static contact angle test, Fourier transform infrared spectrometry and thermogravimetric analysis, and the antibacterial ability to S. aureus and E. coli were also investigated. The results show that the addition of Hc causes increase in the diameter of nanofibers, increases its static contact angle by approximately 20° and decreases its wettability, slightly decreases its thermostability, and imparts good substrate oxidation under visible light. The antibacterial effect against S. aureus and E. coli reached 99.97% and 54.41% under light conditions, respectively.

Key words: hypocrellin, poly(methyl methacrylate-co-methacrylic acid), nanofiber, electrospinning, photodynamic antibacterial property

CLC Number: 

  • TQ342

Fig.1

SEM images of nanofibrous membranes with different Hc concentrations(×5 000)"

Tab.1

Diameters of PM and Hc-PM nanofibrous membrances"

Hc质量分数/% 平均直径/nm 直径标准差/nm 接触角/(°)
0.0 337.25 123.44 109.2
0.1 358.20 146.28 129.2
0.3 398.20 86.83 127.3
0.5 500.61 182.98 131.4

Fig.2

UV-vis spectra of Hc solution and nanofibrous membranes"

Fig.3

FT-IR of PM and Hc-PM nanofibrous membranes"

Fig.4

TG(a)and DTG(b)curves of PM and Hc-PM nanofibrous membranes"

Fig.5

EPR signal of TEMPO generated by Hc-PM membrane and TEMP after illumination"

Fig.6

UV-Vis absorption spectra of KI solution photooxidized by Hc-PM nanofibrous membrane"

Fig.7

UV-Vis absorbance of KI solution at 351 nm photooxidized by PM and Hc-PM nanofibrous membranes"

Fig.8

UV-Vis absorbance of KI solution at 351 nm photooxidized by different proportions of Hc-PM membranes"

Tab.2

Antibacterial effect of S. aureus and E. coli using PM and Hc-PM nanofibrous membranes"

Hc质量分数/% 暗室抑菌率/% 光照抑菌率/%
金黄色葡萄球菌 大肠杆菌 金黄色葡萄球菌 大肠杆菌
0.0 4.12±0.19 5.74±1.54 9.28±0.37 11.48±1.94
0.5 0.90±0.05 10.29±1.53 99.97±0.03 54.41±16.72
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