Journal of Textile Research ›› 2021, Vol. 42 ›› Issue (02): 53-59.doi: 10.13475/j.fzxb.20201008107

• Fiber Materials • Previous Articles     Next Articles

Preparation and properties of sodium alginate/krill protein scaffold materials

YIN Juhui1, GUO Jing1,2(), WANG Yan1,2, CAO Zheng1, GUAN Fucheng1,2, LIU Shuxing1   

  1. 1. School of Textile and Material Engineering, Dalian Polytechnic University, Dalian, Liaoning 116034, China
    2. Functional Fiber and Its Composite Materials Engineering Technology Research Center of Liaoning Province, Dalian, Liaoning 116034, China
  • Received:2020-10-29 Revised:2020-11-06 Online:2021-02-15 Published:2021-02-23
  • Contact: GUO Jing E-mail:guojing8161@163.com

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Abstract:

In order to improve the strength and bio-compatibility of sodium alginate based scaffold materials made from polyelectrolyte composite system with sodium alginate (SA) and krill protein (AKP), SA/AKP scaffold materials were prepared by inducing phase separation-chemical cross-linking method at low-temperature. The structural morphology, mechanical properties, porosity, air permeability, water absorption and bio-compatibility of different concentrations of SA/AKP solutions were compared. The results show that when the concentration of SA/AKP sample is 4%, the pore size of the stent is between 20 and 96 μm with uniform and regular shape. The porosity, and absorptive characteristics of liquid and air permeability of the tissue scaffold decreased with the increasing concentration of SA/AKP solutions, and the fracture strength and elongation of the scaffold increased with the increasing concentration of SA/AKP solutions. When the concentration is 4%, the porosity of the scaffold material is 86.4%, the air permeability is 58.9%, while offering high strength and elongation. The cell toxicity grade of the scaffold is 0, indicating excellent biological safety.

Key words: sodium alginate, krill protein, low temperature induced phase separation, scaffold, bio-compatibility, medical textile

CLC Number: 

  • O636.1

Fig.1

Schematic diagram of preparation of SA/AKP scaffold"

Tab.1

Correspondence between cell proliferation rate and cytotoxicity level"

细胞增殖率/% 毒性水平/级
≥100 0
75~99 1
50~74 2
25~49 3
1~24 4
0 5

Fig.2

SEM image of different mass fraction SA/AKP scaffold"

Fig.3

Pore size distribution image of different mass fraction SA/AKP scaffold"

Fig.4

FT-IR spectra of SA and AKP and SA/AKP scaffold"

Fig.5

Porosity and air permeability of different mass fraction SA/AKP scaffold"

Fig.6

Mechanism diagram of air permeability of SA/AKP scaffold"

Fig.7

Liquid absorbency of different mass fraction SA/AKP scaffold"

Fig.8

Mechanism diagram of liquid absorption of SA/AKP scaffold"

Fig.9

Mechanical properties of different different mass fraction SA/AKP scaffold"

Fig.10

Cytotoxicity of different mass fraction of SA/AKP scaffolds"

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