Journal of Textile Research ›› 2022, Vol. 43 ›› Issue (08): 60-66.doi: 10.13475/j.fzxb.20210702607

• Textile Engineering • Previous Articles     Next Articles

Preparation and properties of silk fibroin/poly(l-lactic acid) nanofiber yarns-based tendon patches

LIU Jiao, CHEN Shaojuan, WU Shaohua()   

  1. College of Textiles & Clothing, Qingdao University, Qingdao, Shandong 266071, China
  • Received:2021-07-07 Revised:2022-02-11 Online:2022-08-15 Published:2022-08-24
  • Contact: WU Shaohua E-mail:shaohua.wu@qdu.edu.cn

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Abstract:

Textile tendon patches made of pure micro yarn structure has low biological activity, high immunogenicity and is non-biodegradable. Several nano-structured tendon patches with great bioabsorbability were fabricated by weaving with optimized patch material and structure. The weft yarn was constructed with the several different types of silk fibroin (SF)/poly(l-lactic acid) (PLLA) nanofiber yarns, the warp yarn was all composed of traditional PLLA microfiber yarns, and the two sets of yarns were interweaved into patches through the weaving process. The effects of the SF and PLLA mass ratio of nanofiber yarns on the morphology, physicochemical and biological properties of such patches were systematically investigated. The results showed that the crystal diffraction appeared at about 16.4°, and crystallinity and mechanical properties of the patches decreased gradually with the increase of SF content. The breaking loads of all tendon patches were found to be higher than 100 N, meeting the requirement of practical application. The biological tests showed that cell adhesion and proliferation ability of the patches gradually improved with the increase of SF content.

Key words: medical textiles, tendon patch, nanofiber yarn, silk fibroin, poly(l-lactic acid)

CLC Number: 

  • TS101.4

Fig.1

SEM images of nanofiber yarns-based tendon patches with different SF/PLLA mass ratios"

Fig.2

Nanofiber diameter of nanofiber yarns-based tendon patches with diverse SF/PLLA mass ratios"

Fig.3

Orientation distribution of nanofiber yarns-based tendon patches with diverse SF/PLLA mass ratios"

Fig.4

FT-IR (a) and XRD (b) curves of nanofiber yarns-based tendon patches with diverse SF/PLLA mass ratios"

Fig.5

Load-elongation curves of nanofiber yarns- based tendon patches with diverse SF/PLLA mass ratios"

Tab.1

Mechanical properties of SF/PLLA nanofiber yarns-based tendon patches with diverse SF/PLLA mass ratios"

SF与PLLA
质量比		 断裂载
荷/N		 断裂伸
长率/％		 断裂强
度/MPa		 初始模
量/MPa
0∶100 220.03±4.01 23.83±1.62 26.82±1.96 460.72±18.77
20∶80 213.45±7.07 23.84±1.06 25.59±1.17 421.46±36.23
35∶65 177.81±5.23 23.86±0.69 22.23±0.66 394.82±35.49
50∶50 113.38±1.78 24.44±0.37 14.14±0.28 303.66±40.13

Fig.6

Phalloidin staining images of nanofiber yarns-based tendon patches with diverse SF/PLLA mass ratios"

Fig.7

Cell adhesion SEM images of nanofiber yarns-based tendon patches with diverse SF/PLLA mass ratios"

Fig.8

Absorbance values of nanofiber yarns-based tendon patches with diverse SF/PLLA mass ratios"

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