Journal of Textile Research ›› 2022, Vol. 43 ›› Issue (03): 38-43.doi: 10.13475/j.fzxb.20211109806

• Invited Column: Biomedical Textiles • Previous Articles     Next Articles

Design and in-vitro mechanical property analyses of sling for female stress urinary incontinence

FANG Meiqi1,2, WANG Qian1,2, LI Yan1,2,3, LI Chaojing1,2,3(), LI Hao4, WANG Lu1,2,3   

  1. 1. College of Textiles, Donghua University, Shanghai 201620, China
    2. Key Laboratory of Textile Science & Technology, Ministry of Education, Donghua University, Shanghai 201620, China
    3. Key Laboratory of Textile Industry for Biomedical Textile Materials and Technology, Donghua University, Shanghai 201620, China
    4. Shanghai Hongyu Medical Tech Co., Ltd., Shanghai 201400, China
  • Received:2021-11-24 Revised:2022-01-04 Online:2022-03-15 Published:2022-03-29
  • Contact: LI Chaojing E-mail:lcj@dhu.edu.cn

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Abstract:

To improve the postoperative erosion of female stress urinary incontinence, a sling with laser-cut diamond-shaped pores and a sling with rectangular pore shapes and self-locking edge were designed. The mesh width, thickness, density, ratio of course density to wale density, pore size, porosity, and effective porosity were characterized and analyzed. The test results of the uniaxial tension and constant load tension test, and the long-term effectiveness and the shrinkage of the two types of slings were discussed and studied. The results show that the two slings are light-weight with large pores, meeting the requirements of high effective porosity, and there is no significant difference between the two in breaking strength and elongation. However, the elastic modulus and flexural stiffness of rectangular mesh sling are obviously larger than that of diamond mesh sling, having higher effective porosity, better dimensional stability and more significant supporting effect of urethral wall under both 2.5 and 16 N/cm loading. The flexibility of the slings would need further improvement.

Key words: sling for female stress urinary incontinence, tension-free mid-urethral sling procedure, medical textiles, fabric structure, mechanical property in-vitro

CLC Number: 

  • TS181

Fig.1

Warp knitting morphological structures and lapping movements. (a) Warp knitting morphological structures of sling A; (b) Lapping movements of sling A; (c) Warp knitting morphological structures of sling B; (d) Lapping movements of sling B"

Fig.2

Examples of mesh pore and pore size measurement of sling A(a) and sling B(b)"

Tab.1

Parameters of mesh pore (P<0.05)"

样品 最大网孔间距/mm 孔隙率/% 有效孔隙率/%
吊带A 1.55±0.08 67.82±0.70 55.62±0.12
吊带B 1.88±0.06 73.55±2.50 57.17±1.00

Tab.2

Parameters of sling structure"

样品 宽度/cm 厚度/mm 面密度/
(g·m-2)		 横密/
(纵行·cm-1)		 纵密/
(横列·cm-1)		 线圈密度/
(个·cm-2)		 密度对比
系数K
吊带A 1.29±0.10 0.369±0.001 46.4 9 9 81 1
吊带B 1.69±0.10 0.497±0.010 40.0 7 18 126 0.39

Fig.3

Representative stress-strain curves of sling A(a) and sling B(b)"

Fig.4

Comparison of axial tensile properties of sling A and sling B"

Fig.5

Macro images of axial tensile properties of sling A (a) and sling B (b)"

Tab.3

Comparison of constant-load test of sling A and sling B"

负荷/
(N·cm-1)		 孔隙率/% 有效孔隙率/% 横向皱缩率/% 塑性变形率/% 弹性回复率/%
吊带A 吊带B 吊带A 吊带B 吊带A 吊带B 吊带A 吊带B 吊带A 吊带B
0 67.82±0.7 73.55±2.5* 55.62±0.1 57.17±1.0* — — — — — —
2.5 57.67±1.8 67.38±1.2* 38.80±2.7 47.87±2.7* 9.44±0.4 4.97±2.2* 1.57±0.2 0.10±0.1* 73.94±5.0 77.87±7.0
16 45.85±0.5 59.68±1.1* 14.23±2.3 43.46±1.1* 35.56±1.5 37.28±2.1 10.06±0.5 11.79±1.9 56.25±2.0 57.30±3.0

Tab.4

CCK-8 tests of L929 at 72 h (P>0.05)"

样品 OD值 相对细胞活力/%
空白对照 1.61±0.03 —
吊带A 1.50±0.03 93.21±0.04
吊带B 1.47±0.04 91.52±0.04
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