Abstract: Silk,wool and silk/wool blended fabrics were dyed with Lanaset serial dyes,and the effect of dyeing process conditions on the color difference between silk and wool of the dyeing was studied.The optimal union dyeing process has been determined through orthogonal experiment,i.e.pH=4,with 10% of ammonium sulfate,and 10 g/L of sodium sulfate,at 80 ℃ for 50 min.