Abstract: A new kind of functional cellulose fiber grafted with β-cyclodextrin(βCD) was synthesized in an alkaline medium,which contained an inclusion complex of resorcinol drug.The stability constant and apparent thermodynamic parameter of the inclusion complex under different temperatures were determined,and its stability and releasing behavior in aqueous solution were also examined.It is observed that inclusion reaction which is affected by van der waals is one kind of exothermic.The inclusion complex contained in the fiber is rather stable under(25 ℃),and its release of resorcinol reaches nearly optimum state is around(36 ℃,) which is the normal temperature of the human body.