Abstract: For optimizing the process conditions of enzymatic finishing of the hand-made ramie cloth,high efficiency mixture of xylanase and cellulase was employed in the enzyme finishing of the cloth.The effects of enzyme dosage,bath ratio,temperature,pH value and duration of treatment on the finishing result were investigated.It demonstrated that the optimized process conditions of enzymatic finishing of the hand-made ramie cloth are as follows: 0.5% xylanase,0.5%～2% cellulase,bath ratio,1∶15,pH value at the range of 4.5～5.0,and treating at(50 ℃) for 1 hour.Among the factors influencing the finishing,cellulase concentration is in the first place,and followed by original pH value,the last is bath ratio.