Abstract: To study the relationship between the content of silver-plated fibers in fabrics and the antibacterial performance of the fabrics, five sets of samples with common polyester yarns and silver-plated polyamide yarns were manufactured for the experiment, a qualitative antibacterial test with flask-shaking method was performed and compared for fabrics with different content of silver-plated fibers. The results show that fabrics with silver-plated fibers have good antibacterial effect, and the bacterial inhibition rate will be improved as the content of silver-plated fibers increasing. When the content of silver-plated fibers is 3.6%, the bacterial inhibition rate for coli form and golden staphylococcus will reach to 76.92% and 99.36%, the antibacterial effect of silver-plated fibers to golden staphylococcus is better than coli form; When the content of silver-plated fibers is higher than 11.99%, the fabrics have better antibacterial properties for the two bacteria and the bacterial inhibition rates are higher than 99%.