Abstract: Spider silk is an excellent fibre with combination of tensile strength and elasticity, but the isolation of large amount of spider silk in nature is difficult. Such superior biomaterials could be useful for industrial and medical purposes. In this study, We induce spider dragline silk (MaSp1) gene into the chromosome of silkworm by piggyBac transgenic vector. The result showed the trangeic silkworm can produce a new composite silk fiber that contains MaSp1 protein. It also suggested that produce many kinds of new composite protein fiber material by transgenic silkworm is feasible.

Key words: transgenic silkworm , spider silk , composite silk