Abstract: A method for the determination of triclosan and triclocarban in textiles was developed by solid phase extraction and liquid chromatography-tandemed mass spectrometry (SPE-LC-MS/MS). The sample was extracted with dichloromethane by ultrasonic and clean-up on a C18 SPE cartridge. The analyte was determined by an electrospray ionization tandem mass spectrometry in multiple reactions monitoring (MRMs) mode. The qualitative and quantitative analyses was based on the retention times and characteristic ion pairs consisting of one parent ion and fragment ions of the analyte. Linearities in the range of 1.0~50.0 ng/mL and 0.25~50.0 ng/mL for triclosan and triclocarban, respectively. The limits of quantification (LOQs) for triclosan and triclocarban were 1.0 and 0.25 μg/kg, respectively, the average recoveries were in the range of 84.5% ~ 108.2 % with the relative standard deviations below 8.1 %. This method is accurate and sensitive, and it is suitable for the analysis of triclosan and triclocarban in textiles.

Key words: liquid chromatography-tandemed mass spectrometry, solid-phase extraction, triclosan, triclocarban, textiles