Abstract:

Tussah fibroin (TSF)/poly lactic acid (PLA) composite nanofiber yarns with different ratio of TSF to PLA were prepared to fabricate tissue scaffold with great mechanical, good maneuverability and biological property by conjugate electro-spinning device. The scanning electronic microscope (SEM) and infrared spectroscopy (FTIR) and cell cultured in vitro were used to character the morphology, second structure and biological property of the yarns separately. The result indicates that the yarn with the ratio of TSF to PLA of 1:9 gain smaller diameter, uniform evenness, as well as less hairiness and better mechanical. After cultured in vitro for different time, the yarn with the ratio of TSF to PLA of 1:9 as tissue scaffold keep healthy and more cell count to make the PLTF yarn appropriate scaffold.