Journal of Textile Research ›› 2019, Vol. 40 ›› Issue (10): 7-12.doi: 10.13475/j.fzxb.20181003306

• Fiber Materials • Previous Articles     Next Articles

Preparation and antibacterial activity of silk fibroin/chitosan microspheres

ZHANG Zhibin1,2, LI Gang1,2(), MAO Senxian3, LI Xunxun3, CHEN Yushuang3, MAO Qingshan3, LI Yi4, PAN Zhijuan1,2, WANG Xiaoqin1,2   

  1. 1. College of Textile and Clothing Engineering, Soochow University, Suzhou, Jiangsu 215123, China
    2. National Engineering Laboratory for Modern Silk, Soochow University, Suzhou, Jiangsu 215123, China
    3. Zhejiang Truelove Vogue Co., Ltd., Jinhua, Zhejiang 322000, China
    4. School of Materials, The University of Manchester, Manchester M139PL, UK
  • Received:2018-10-18 Revised:2019-05-11 Online:2019-10-15 Published:2019-10-23
  • Contact: LI Gang E-mail:tcligang@suda.edu.cn

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Abstract:

In order to develop a natural and harmless antibacterial finishing agent which is beneficial to human body, silk fibroin/chitosan microspheres were prepared by emulsion polymerization. The microscopic morphology, chemical structure, thermal stability and antibacterial properties of the microspheres with different ratios of silk fibroin and chitosan were examined. The results show that the silk fibroin mass fraction is 6%, the chitosan mass fraction is 3%, and the volume ratio of chitosan to silk fibroin is 1∶2, the microspheres have a spherical shape and smooth surface with particle size between 0.4 to 1.4 μm. In addition, it has a good antibacterial effect against Escherichia coli and Staphylococcus aureus, with the antibacterial ratio of(82 ± 4.2)% and(80 ± 2.6)%, respectively. The secondary structure of the microspheres changes from silk I to silk II, and the initiation temperature of thermal decomposition is higher than 250 ℃, showing good thermal stability.

Key words: silk fibroin, chitosan, microsphere, antibacterial property, emulsion polymerization

CLC Number: 

  • TS141.8

Fig.1

SEM images of microspheres with different volume ratios of CS and SF"

Fig.2

X-ray diffraction of microspheres with different volume ratios of CS and SF"

Fig.3

FT-IR spectra of CS, SF and CS/SF microspheres"

Fig.4

TG curves of CS, SF and CS/SF microspheres"

Fig.5

Antibacterial effects of SF(a)and CS/SF(b) microspheres on Escherichia coli"

Fig.6

Antibacterial effects of SF(a)and CS/SF(b) microspheres on Staphylococcus aureus"

Fig.7

Antibacterial properties of microspheres with different volume ratios of CS and SF"

Fig.8

Formation mechanism of SF/CS microspheres"

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