Journal of Textile Research ›› 2020, Vol. 41 ›› Issue (09): 183-190.doi: 10.13475/j.fzxb.20191205108

• Column: Biomedical Textile Materials and It′s Products • Previous Articles     Next Articles

Clinical applications of silver containing alginate wound dressings

QIN Yimin1,2()   

  1. 1. College of Material and Textile Engineering, Jiaxing University, Jiaxing, Zhejiang 314001, China
    2. State Key Laboratory of Bioactive Seaweed Substances, Qingdao, Shandong 266400, China
  • Received:2019-12-23 Revised:2020-05-26 Online:2020-09-15 Published:2020-09-25

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Abstract:

In order to promote the applications of silver containing alginate fibers and develop functional wound dressings with high absorbency and strong antimicrobial properties, this paper introduced the main varieties, production methods, product properties and applications of silver containing fibers and wound dressings in the international market, and summarized their efficacy in reducing the re-infection ratio through control of wound infection, relieving pain through suppression of bacteria growth, shortening treatment cycle through the promotion of healing and reducing the treatment cost and other outstanding benefits. Combining the latest clinical research results from around the world, this paper outlined the clinical values of silver containing alginate fibers and wound dressings in the management of infected wound, burn wound, clinical incision, diabetic foot ulcer, leg ulcer, pressure sore and other types of wounds.

Key words: alginate fiber, wound dressing, biomedical material, silver ion, antimicrobial property

CLC Number: 

  • TS131.9

Tab.1

Main silver containing alginate wound dressings in international market"

产品名称 制造商 基础材料 银化合物
Acticoat Absorbent Smith & Nephew 海藻酸盐纤维复合聚乙烯膜 纳米银
Algicell Ag Derma Sciences 海藻酸钙纤维 银离子
Algidex Ag DeRoyal 海藻酸钙纤维复合泡绵 银离子
Algisite Ag Smith & Nephew 海藻酸钙纤维 银离子
Askina Calgitrol Ag B. Braun 海藻酸钙纤维复合泡绵 银离子
Invacare Silver Alginate Invacare 海藻酸盐与CMC共混纤维 磷酸锆钠银
Maxorb Extra Ag Medline 海藻酸盐与CMC共混纤维 磷酸锆钠银
Melgisorb Ag M?lnlycke 海藻酸盐与CMC共混纤维 磷酸锆钠银
Restore Calcium Alginate Hollister Woundcare 海藻酸钙纤维 银离子
SeaSorb Ag Coloplast 海藻酸盐与CMC共混纤维 磷酸锆钠银
Silvercel & Silvercel Non Adherent Systagenix 海藻酸盐与CMC共混纤维复合不粘层 镀银锦纶纤维
Silverlon Calcium Alginate Argentum Medical 海藻酸钙纤维 镀银锦纶纤维核心层
Tegaderm Alginate Ag 3 M 海藻酸盐与CMC共混纤维 磷酸锆钠银
UrgoSorb Silver Urgo 海藻酸盐与CMC共混纤维 磷酸锆钠银

Fig.1

Mechanism of action for silver containing alginate fiber wound dressing"

Tab.2

Comparison of change in wound infection"

组别 例数 伤口细菌转阴例数
治疗7 d后 治疗14 d后 治疗21 d后
观察组 62 19 28 56
对照组 62 11 20 39

Tab.3

Comparison of pain during dressing change"

组别 疼痛评分
换药前 换药后3 d 换药后7 d 换药后15 d
观察组 5.47±1.22 3.08±0.54 2.66±0.53 1.96±0.41
对照组 5.89±1.54 5.53±0.68 4.88±0.75 2.12±0.72

Tab.4

Comparison of time required for dressing change and wound healing"

组别 例数 换药时间/d 创面愈合时间/d
观察组 40 7.69±2.19 10.57±4.38
对照组 40 13.57±3.48 17.58±4.50

Tab.5

Comparison of wound recovery parameters"

组别 肉芽覆盖时间/d 肉芽痊愈时间/d 愈合时间/d
观察组 3.75±1.20 6.28±1.39 11.70±2.24
对照组 6.85±2.04 8.39±1.54 14.57±3.86

Tab.6

Comparison of wound management parameters"

组别 伤口治愈
时间/d		 换药
次数		 换药
治疗费/万元		 住院治疗
费/万元
观察组 47.2±3.3 12.5±2.4 0.6±0.4 2.6±1.7
对照组 68.3±5.8 32.8±6.3 0.5±0.3 4.1±2.3
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