Journal of Textile Research ›› 2021, Vol. 42 ›› Issue (05): 16-22.doi: 10.13475/j.fzxb.20200605207

• Fiber Materials • Previous Articles     Next Articles

Preparation and performance of polyvinyl alcohol/sodium alginate/berberine medical dressing

WANG Chunhong1(), LI Ming1, LONG Bixuan1, CAI Yingjie2, WANG Lijian1, ZUO Qi1   

  1. 1. School of Textile Science and Engineering, Tiangong University, Tianjin 300387, China
    2. College of Textile and Garments, Hebei University of Science and Technology, Shijiazhuang, Hebei 050080, China
  • Received:2020-06-17 Revised:2021-01-03 Online:2021-05-15 Published:2021-05-20

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Abstract:

In order to improve the antibacterial and water resistance of polyvinyl alcohol (PVA)/sodium alginate (SA) medical dressings, berberine (BR) was used as a natural antibacterial agent to load on the medical dressing. The PVA/SA/BR nanofiber membrane was prepared by electrostatic spinning, and the membrane was cross-linked in calcium chloride absolute ethanol solution. The chemical structure, antibacterial performance, liquid absorption and mechanical properties of the PVA/SA/BR nanofiber membrane were characterized and analyzed. The results show obvious beads of BR in PVA/SA nanofiber,which combine well with PVA/SA. After cross-linking with calcium chloride, the PVA/SA/BR nanofiber membrane changes from mesh to smooth membrane. When the mass fraction of berberine is 6%, the breaking strength of the PVA/SA/BR nanofiber membrane is 1.76 MPa, and the antibacterial rates for Escherichia coli and Staphylococcus aureus are 99.41% and 97.89% repspectively. When the mass fraction of calcium chloride is 4% and the cross-linking time is 4 h, the breaking strength of the PVA/SA/BR nanofiber membrane is 4.17 MPa and the liquid absorption rate is 1 257%.

Key words: medical dressing, berberine, calcium chloride cross-linking, antibacterial property, water resistance, nanofiber membrane

CLC Number: 

  • TQ340.64

Fig.1

Surface morphology (×8 000) and diameter distribution of PVA/SA/BR nanofiber membranes withdifferent mass fraction of BR"

Fig.2

Infrared spectra of BR、PVA/SA and PVA/SA/BR nanofiber membranes"

Fig.3

Tensile strength and elongation at break of PVA/SA/BR nanofiber membranes with different mass fraction of BR"

Fig.4

Antibacterial rate of PVA/SA/BR nanofiber membranes against Escherichia coli and Staphylococcus aureus"

Fig.5

Antibacterial effect of PVA/SA/BR nanofiber membranes against Escherichia coli (a) and Staphylococcus aureus (b)with different mass fraction of BR"

Fig.6

SEM images of PVA/SA/BR after crosslinking with calcium chloride at different concentrations (×5 000)"

Fig.7

Liquid absorption ratio of PVA/SA/BR nanofiber membranes crosslinked with different concentrations of calcium chloride"

Fig.8

Liquid absorption ratio of PVA/SA/BR nanofiber membranes at different cross-linking time"

Fig.9

Mechanical properties of PVA/SA/BR with different cross-linking times"

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