Abstract: The aim of this work was to achieve a cushioning warp-knitted spacer fabric with good support and distribution of weight, the indentation force deflection (IFD) property of different warp-knitted spacer fabrics were studied. 13 specimens were knitted on double needle bar Rachel machine by changing the lengthwise density of the fabric, lapping angle and diameter of pile yarn and the distance of two comb bars. The compression stress and strain behaviors of samples were tested. The 25% IFD, 65% IFD and support factor are used to evaluate the IFD property of the fabric. How the density, lapping angle and diameter of pile yarn and the distance of the two comb bars influence the IFD property is analyzed. Preliminary results reveal that the period of give-in is the most important period in the compression study of spacer fabric, and with rational selecion of construction parameters, optimal cushioning warp-knitted spacer fabric can be manufactured.