Abstract: A effective method for determination of triclosan in textiles by solid phase extraction - high performance liquid chromatography was developed. The samples were used by Ultrasonic Extraction, cleaned and enriched by a Sep-Pak? Vac Silica solid phase extraction(SPE) cartridge. The separation was performed on a Kromasil C18 column（250 mm × 4.6 mm i.d., 5 μm） by using the mobile phase consisting of H2O/CH3CN(15/85, V/V) . Detection was performed by 280 nm using extenal standard method. The result of experiment shows that calibration curve of triclosan was linear within the range of 0.1~20.0 mg/kg , the limit of detection was found to be 0.01 mg/kg,and the limit of quantification was found to be 0.05 mg/kg. The extraction recoveries were between 94.0% and 100.4% and the RSDs were 2.0%~4.4%. This method is found to be simple, quick, accurate, little interferential for the determination of triclosan residue in textiles.

Key words: textiles, triclosan, high performance liquid chromatography, solid phase extraction