In order to weave textiles with the durability in special environments, poly(fluorinated ethylene-propylene)(FEP) yarns were prepared from FEP fiber by twisting and doubling. The plain weave fabric of FEP with the width of 250 mm and the thickness of 0.51 mm was woven by a semi-automatic loom. Electronic tensile testing machine, dynamic contact angle tester, fabric air permeability tester, fabric moisture permeability tester, abrasion tester, ultraviolet condensation aging test box, differential scanning calorimeter, X-ray diffractometry and Fourier transform infrared spectroscopy were applied to analyze and characterize the properties of yarns and fabrics. The results show that FEP yarns have good mechanical properties and hydrophobicity. FEP fabric have excellent mechanical properties, high-temperature resistance and excellent chemical resistance and aging resistance. The thermal performance, crystalline structure, chemical structure and mechanical properties of the fabrics treated with acid, alkali and organic solvents have no significant change. The mechanical properties of the FEP fabrics treated under UV irradiation have no significant change, showing the feasible application of FEP fiber fabric in special environments.